来自圭亚那破布木的两种新的细胞毒性化合物。
Two new cytotoxic compounds from Tapirira guianensis.
作者信息
David J M, Chávez J P, Chai H B, Pezzuto J M, Cordell G A
机构信息
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.
出版信息
J Nat Prod. 1998 Feb;61(2):287-9. doi: 10.1021/np970422v.
PMID:9514013
Abstract
Two new cytotoxic compounds, 2-[10(Z)-heptadecenyl]-1,4-hydroquinone (1) and (4R,6R)-dihydroxy-4-[10(Z)-heptadecenyl]-2-cyclohexenone (2) have been isolated from a MeOH extract of seeds of Tapirira guianensis. The structures were established through spectral analysis of the isolates and their derivatives.
摘要
从圭亚那塔皮里拉种子的甲醇提取物中分离出两种新的细胞毒性化合物，2-[10(Z)-十七碳烯基]-1,4-对苯二酚(1)和(4R,6R)-二羟基-4-[10(Z)-十七碳烯基]-2-环己烯酮(2)。通过对分离物及其衍生物的光谱分析确定了其结构。
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