手性4-烷基-4-羟基环己烯酮的通用合成方法。
General synthesis for chiral 4-alkyl-4-hydroxycyclohexenones.
作者信息
Hoarau Christophe, Pettus Thomas R R
机构信息
Department of Chemistry and Biochemistry, University of California at Santa Barbara, 93106-9510, USA.
出版信息
Org Lett. 2006 Jun 22;8(13):2843-6. doi: 10.1021/ol061000s.
Abstract
[reaction: see text] Some selective transformations of resorcinol-derived cyclohexadienone are reported. Efforts led to a structure reported to display anticancer properties. On the basis of the results, the structures for natural products reported to contain a 4,6-dihydroxy-4-alkyl-cyclohexenone nucleus are corrected.
摘要
[反应：见正文] 报道了间苯二酚衍生的环己二烯酮的一些选择性转化。研究工作得到了一种据报道具有抗癌特性的结构。基于这些结果，对据报道含有4,6 - 二羟基 - 4 - 烷基 - 环己烯酮核的天然产物的结构进行了修正。
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