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普伐他汀诱发的苔藓样药疹。

Pravastatin-induced lichenoid drug eruption.

作者信息

Keough G C, Richardson T T, Grabski W J

机构信息

Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200, USA.

出版信息

Cutis. 1998 Feb;61(2):98-100.

PMID:9515217
Abstract

Although drug eruptions caused by pravastatin and other lovastatin analogs have previously been described, reports of lichenoid eruptions are rare. We report a patient whose lichenoid lesions developed after initiation, resolved on discontinuation, and reappeared on rechallenge with pravastatin therapy. A brief review of lichenoid drug eruptions and skin lesions due to 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors is discussed.

摘要

尽管此前已有关于普伐他汀及其他洛伐他汀类似物引起药物疹的报道,但苔藓样疹的报告却很罕见。我们报告了一名患者,其苔藓样皮损在开始使用普伐他汀后出现,停药后消退,再次使用普伐他汀治疗时又重新出现。本文还简要讨论了3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂引起的苔藓样药物疹及皮肤损害。

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