Silverstein L H, Garnick J J, Szikman M, Singh B
Department of Periodontics, Medical College of Georgia, Augusta, USA.
Gen Dent. 1997 Jul-Aug;45(4):371-6; quiz 379-80.
This review discusses the etiology and treatment of gingival hyperplasia. It cites evidence that medications such as phenytoin, an anticonvulsant; cyclosporine, an immunosuppressant; and numerous calcium channel blocking agents have been shown clinically and histologically to produce analogous gingival enlargements. A multiphasic approach to treating disfiguring gingival hyperplasia through mechanical and chemical plaque control, in conjunction with the surgical removal of the hyperplastic tissue, is discussed.
本综述讨论了牙龈增生的病因及治疗方法。文中引用的证据表明，抗惊厥药苯妥英、免疫抑制剂环孢素以及多种钙通道阻滞剂等药物，在临床和组织学上均已显示可导致类似的牙龈增生。本文还讨论了通过机械和化学菌斑控制，结合手术切除增生组织，来治疗毁容性牙龈增生的多阶段方法。
