Katz J, Givol N, Chaushu G, Taicher S, Shemer J
Department of Oral Medicine, Sheba Medical Center, Tel Hashomer, Israel.
J Clin Periodontol. 1997 Mar;24(3):180-2. doi: 10.1111/j.1600-051x.1997.tb00488.x.
Vigabatrin is a relatively new medication used in the treatment of epilepsia. The present report concerns the use of vigabatrin by a 19-year-old woman. The patient manifested marked gingival overgrowth compatible clinically and histologically with the overgrowth induced by phenytoin, cyclosporine and calcium channel blockers. This is the 1st report of vigabatrin-induced gingival overgrowth. Clinicians should be aware of similar lesions in patients using new anticonvulsants.
氨己烯酸是一种用于治疗癫痫的相对较新的药物。本报告涉及一名19岁女性使用氨己烯酸的情况。该患者表现出明显的牙龈增生，在临床和组织学上与苯妥英钠、环孢素和钙通道阻滞剂引起的增生相符。这是关于氨己烯酸引起牙龈增生的首例报告。临床医生应注意使用新型抗惊厥药的患者中出现的类似病变。
