Murata I, Ogami Y, Nagai Y, Furumi K, Yoshikawa I, Otsuki M
Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine, Kitakyushu.
Am J Gastroenterol. 1998 Mar;93(3):449-51. doi: 10.1111/j.1572-0241.1998.00449.x.
A 59-yr-old man with carcinoma of the stomach, concurrent acquired hyperkeratosis (tylosis) of the palms and soles, and acanthosis of the esophageal mucosa is reported. He presented the tylosis and esophageal lesions when the carcinoma was evident. Resection of the stomach resulted in diminution of the skin and esophageal lesions. The association of sporadic tylosis and carcinoma of the stomach is extremely rare. This is the first case report documenting the association of gastric cancer, tylosis, and acanthosis of the esophageal mucosa.
报告了一名59岁男性，患有胃癌，同时伴有掌跖后天性角化过度（胼胝症）和食管黏膜棘皮症。在胃癌明显时，他出现了胼胝症和食管病变。胃切除术后，皮肤和食管病变有所减轻。散发性胼胝症与胃癌的关联极为罕见。这是第一例记录胃癌、胼胝症和食管黏膜棘皮症关联的病例报告。
