Medzhitov R, Janeway C A
Section of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Curr Opin Immunol. 1998 Feb;10(1):12-5. doi: 10.1016/s0952-7915(98)80024-1.
Research over the past few years has begun to provide significant advances in our understanding of the interplay between the innate and adaptive immune systems. New findings in several model systems reveal remarkable parallels and conservation of ancient host defense pathways in organisms separated by over a billion years of evolution.
过去几年的研究已开始在我们对先天性免疫系统和适应性免疫系统之间相互作用的理解上取得重大进展。几个模型系统中的新发现揭示了在经过超过十亿年进化而分隔的生物体中，古老宿主防御途径存在显著的相似性和保守性。
