鸟氨酸脱羧酶抗酶的鸡互补DNA

The chicken cDNA for ornithine decarboxylase antizyme.

作者信息

Drozdowski B, Gong T W, Lomax M I

机构信息

Kresge Hearing Research Institute, Department of Otolaryngology/Head-Neck Surgery, University of Michigan Medical School, Ann Arbor 48109-0648, USA.

出版信息

Biochim Biophys Acta. 1998 Mar 4;1396(1):21-6. doi: 10.1016/s0167-4781(97)00162-0.

DOI:10.1016/s0167-4781(97)00162-0

PMID:9524208

Abstract

Two full length avian cDNAs for ornithine decarboxylase antizyme were isolated from a chicken cochlear cDNA library and differed in length through use of alternative poly(A) addition signals. The chick antizyme protein sequence predicted by translational frameshifting of the mRNA is 216 amino acids long and is more similar to Xenopus antizyme than to the mammalian protein.

摘要

从鸡耳蜗cDNA文库中分离出两个完整长度的鸟氨酸脱羧酶抗酶禽类cDNA，它们通过使用不同的聚腺苷酸化信号而长度不同。通过mRNA的翻译移码预测的鸡抗酶蛋白序列长216个氨基酸，与非洲爪蟾抗酶的相似性高于与哺乳动物蛋白的相似性。