Cisar J O, Takahashi Y, Ruhl S, Donkersloot J A, Sandberg A L
Laboratory of Microbial Ecology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Adv Dent Res. 1997 Apr;11(1):168-75. doi: 10.1177/08959374970110010801.
Oral surfaces are bathed in secretory antibodies and other salivary macromolecules that are potential inhibitors of specific microbial adhesion. Indigenous Gram-positive bacteria that colonize teeth, including viridans streptococci and actinomyces, may avoid inhibition of adhesion by host secretory molecules through various strategies that involve the structural design and binding properties of bacterial adhesins and receptors. Further studies to define the interactions of these molecules within the host environment may suggest novel approaches for the control of oral biofilm formation.
口腔表面浸浴在分泌性抗体和其他唾液大分子中，这些物质是特定微生物黏附的潜在抑制剂。在牙齿上定植的天然革兰氏阳性菌，包括草绿色链球菌和放线菌，可能通过各种策略避免被宿主分泌分子抑制黏附，这些策略涉及细菌黏附素和受体的结构设计及结合特性。进一步研究以确定这些分子在宿主环境中的相互作用，可能会为控制口腔生物膜形成提供新方法。
