Billings R J, Adair S M, Shields C P, Moss M E
Eastman Dental Center, Rochester, New York, USA.
Pediatr Dent. 1998 Jan-Feb;20(1):17-24.
Intraoral fluoride-releasing (IFR) devices provide elevated levels of fluoride in the mouth for extended periods of time. However, retention and protection of the devices have posed major challenges for clinical applications. The objectives of this study were to develop new methods for retaining and protecting IFR devices in the mouth and to assess their effects on salivary fluoride levels and distribution in adolescents.
Four different IFR systems (combinations of an IFR device and its retainer) were evaluated in four groups of 10 adolescents each, 12-15 years of age, for a period of six months. Each child wore two IFR systems of a given type affixed to the buccal surface of each permanent maxillary first molar. Unstimulated saliva samples were collected at each clinical examination and analyzed for fluoride.
A significant increase in salivary fluoride concentration from a baseline mean of 0.07-0.69 microgram/mL was observed on day 14 postinsertion. IFR system retention was 85% after 6 months and, of the systems retained, 100% were functional.
These findings suggest that IFR devices can be successfully protected and retained in the mouth for prolonged periods of time.
口腔内释氟（IFR）装置可在较长时间内使口腔中的氟水平升高。然而，装置的固位和保护对临床应用构成了重大挑战。本研究的目的是开发在口腔中固位和保护IFR装置的新方法，并评估其对青少年唾液氟水平及分布的影响。
在四组每组10名12至15岁的青少年中对四种不同的IFR系统（一个IFR装置及其固位体的组合）进行了为期六个月的评估。每个孩子在每颗上颌第一恒磨牙的颊面佩戴两个给定类型的IFR系统。在每次临床检查时收集非刺激性唾液样本并分析其中的氟。
在植入后第14天观察到唾液氟浓度从基线平均值0.07微克/毫升显著增加至0.69微克/毫升。6个月后IFR系统的固位率为85%，在保留的系统中，100%功能正常。
这些发现表明IFR装置能够在口腔中成功地得到保护并长时间固位。
