Murphy N J, Schraer C D, Theile M C, Boyko E J, Bulkow L R, Doty B J, Lanier A P
Alaska Native Medical Center, Anchorage 99508, USA.
Ethn Health. 1997 Nov;2(4):267-75. doi: 10.1080/13557858.1997.9961835.
Determine the prevalence of hypertension in Alaska Natives and evaluate risk factors.
Population-based univariate and multivariate analysis of blood pressure in 1124 Alaska Natives over 20 years of age.
The sample had mean: age 45 years, body mass index 27, systolic pressure 123 mmHg and diastolic pressure 73 mmHg. The age-adjusted rate of hypertension > or = 160/95 mmHg was 9.1% and 6.8% among Athabascan Indians and Yup'ik Eskimos, respectively. After controlling for age and sex there was significantly more hypertension among Athabascan Indians (OR = 1.53, CI = 1.07-2.2, p = 0.019) compared to Yup'ik Eskimos. Race was significantly associated with blood pressure > or = 140/90 when controlled for age and overweight (p = 0.01, OR = 0.78, CI = 0.69-0.95). The presence of hypertension was significantly associated with the following: intake of non-indigenous food (p = 0.01); mechanized activities (p = 0.01); and glucose intolerance in both women (p = 0.043) and men (p = 0.001). Multiple regression analysis revealed age (OR = 1.06, CI = 1.05-1.08) and overweight in both men (OR = 3.02, CI = 1.85-4.93) and women (OR = 2.76, CI = 1.81-4.19) to be significantly associated with BP > or = 140/90.
Hypertension is no longer rare in Alaska Natives and is associated with overweight, non-indigenous diet, mechanized activities, and glucose intolerance.
确定阿拉斯加原住民中高血压的患病率并评估风险因素。
对1124名20岁以上的阿拉斯加原住民的血压进行基于人群的单变量和多变量分析。
样本的平均年龄为45岁，体重指数为27，收缩压为123 mmHg，舒张压为73 mmHg。在阿萨巴斯卡印第安人和尤皮克爱斯基摩人中，年龄调整后的高血压（收缩压≥160 mmHg和舒张压≥95 mmHg）患病率分别为9.1%和6.8%。在控制年龄和性别后，与尤皮克爱斯基摩人相比，阿萨巴斯卡印第安人中的高血压患者明显更多（比值比=1.53，置信区间=1.07 - 2.2，p = 0.019）。在控制年龄和超重因素后，种族与收缩压≥140 mmHg和舒张压≥90 mmHg显著相关（p = 0.01，比值比=0.78，置信区间=0.69 - 0.95）。高血压的存在与以下因素显著相关：非本土食物的摄入（p = 0.01）；机械化活动（p = 0.01）；以及女性（p = 0.043）和男性（p = 0.001）的葡萄糖不耐受。多元回归分析显示，年龄（比值比=1.06，置信区间=1.05 - 1.08）以及男性（比值比=3.02，置信区间=1.85 - 4.93）和女性（比值比=2.76，置信区间=1.81 - 4.19）的超重与收缩压≥140 mmHg和舒张压≥90 mmHg显著相关。
高血压在阿拉斯加原住民中已不再罕见，并且与超重、非本土饮食、机械化活动和葡萄糖不耐受有关。
