希腊克里特岛的假性剥脱流行病学。
Epidemiology of pseudoexfoliation in the island of Crete (Greece).
作者信息
Kozobolis V P, Papatzanaki M, Vlachonikolis I G, Pallikaris I G, Tsambarlakis I G
机构信息
University of Crete, School of Health Sciences, Department of Ophthalmology, Vardinoyannion Eye Institute, Heraklion, Greece.
出版信息
Acta Ophthalmol Scand. 1997 Dec;75(6):726-9. doi: 10.1111/j.1600-0420.1997.tb00640.x.
PURPOSE
To evaluate the pseudoexfoliation (PEX) prevalence in the island of Crete (Greece).
METHOD
Organized visits to various villages, to examine a predetermined number of people born and living in these villages, in collaboration with the local birth register offices.
RESULTS
PEX prevalence in Crete, in people aged 40 years and more, was found to be 16.1% (men: 21.3%, women: 12.6% - Prefecture of: Heraklion 11.5%, Chania 13.4%, Lasithi 16.9%, Rethymnon 27%). 28.8% of PEX-patients presented IOP > 21 mmHg. In unilateral PEX-patients, mean IOP of PEX-eyes was found to be 17.82 mmHg versus 15.6 mmHg in fellow eyes.
CONCLUSION
PEX prevalence was higher in men than in women and increases with age, as does bilaterality. A correlation between increased PEX prevalence and high altitude may exist. PEX is a risk factor for the development of IOP disturbances which seem to appear earlier in women.
目的
评估希腊克里特岛的假性剥脱（PEX）患病率。
方法
与当地出生登记办公室合作，组织对各个村庄进行走访，检查预先确定数量的在这些村庄出生并居住的人。
结果
在克里特岛，40岁及以上人群的PEX患病率为16.1%（男性：21.3%，女性：12.6%——地区情况：伊拉克利翁11.5%，干尼亚13.4%，拉斯ithi16.9%，雷西姆农27%）。28.8%的PEX患者眼压>21 mmHg。在单侧PEX患者中，PEX眼的平均眼压为17.82 mmHg，而对侧眼为15.6 mmHg。
结论
PEX患病率男性高于女性，且随年龄增长而增加，双侧性亦是如此。PEX患病率增加与高海拔之间可能存在关联。PEX是眼压紊乱发展的一个危险因素，且似乎在女性中出现得更早。
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