Symons A L, Taverne A A
Department of Dentistry, University of Queensland, Brisbane, Australia.
Aust Orthod J. 1996 Oct;14(3):168-71.
This report describes a family who demonstrated anomalies of tooth form and eruption of the lower second premolar. Observation of the second premolars remaining in the mother's and father's dentitions included ectopic eruption with impaction and substantial spacing between the first and second premolars. Four siblings were also examined--three boys aged 15, 14 and 12 years, and one girl aged 11 years. Anomalies of the second premolar recorded in the males and female include: congenital absence, ectopic eruption with impaction, delayed eruption and spacing. Associated anomalies included: congenital absence of other permanent teeth and spacing. It appears that the defect in tooth form and eruption is of a genetic origin, affecting both males and females. The condition(s) did not appear to be associated with a syndrome and the human papilloma virus lesions noted in all family members were not considered to be related to the dental defects. This family demonstrated two anomalies of the lower second premolar: congenital absence and disturbance in tooth eruption. The question raised by this case report is whether these two anomalies are inherited as separate traits or whether failure of tooth eruption is a variation in expression of the same genetic factor that results in oligodontia.
本报告描述了一个家族，该家族中出现了下颌第二前磨牙的牙形和萌出异常情况。对留存于父母牙列中的第二前磨牙观察发现，存在异位萌出伴阻生以及第一和第二前磨牙之间有明显间隙。还对四个兄弟姐妹进行了检查，其中三个男孩分别为15岁、14岁和12岁，一个女孩为11岁。在男性和女性中记录到的第二前磨牙异常情况包括：先天性缺失、异位萌出伴阻生、萌出延迟和间隙。相关异常情况包括：其他恒牙先天性缺失和间隙。似乎牙形和萌出方面的缺陷源于遗传，对男性和女性均有影响。这种情况似乎与某种综合征无关，并且在所有家族成员中发现的人乳头瘤病毒病变也被认为与牙齿缺陷无关。这个家族表现出下颌第二前磨牙的两种异常情况：先天性缺失和牙齿萌出障碍。本病例报告提出的问题是，这两种异常情况是作为独立性状遗传，还是牙齿萌出失败是导致少牙畸形的同一遗传因素表达的一种变异。
