胆汁成石过程中的脂质
Lipids in biliary lithogenesis.
作者信息
Singh V, Zaidi S A, Singh V S
机构信息
Department of Biochemistry, L.L.R.M. Medical College, Meerut, India.
出版信息
J Pak Med Assoc. 1997 Oct;47(10):253-5.
Serum and biliary lipoproteins, total cholesterol (Tc) and triglycerides (TG) were measured in patients with gallstones and in those without gallstones. Serum and biliary LDLc, TG and Tc were significantly higher (P < 0.001) in cases having gall stones than those without stones while HDLc were low (P < 0.001) in those with stones. No difference was found in very low density lipoproteins (VLDLc) in the two groups. Present data showed that there is a statistically significant correlation of serum and biliary lipoproteins specifically LDLc and HDLc (r = +.67 and r = +.56). This report shows that serum HDLc (67.42%) and LDLc (70.28%) play a more critical role in comparison to total cholesterol (59.43%) and triglyceride (57.15%) levels in the formation of gallstone.
对患有胆结石的患者和未患胆结石的患者进行了血清和胆汁脂蛋白、总胆固醇（Tc）及甘油三酯（TG）的检测。胆结石患者的血清和胆汁低密度脂蛋白胆固醇（LDLc）、TG及Tc显著高于（P < 0.001）无结石患者，而有结石患者的高密度脂蛋白胆固醇（HDLc）较低（P < 0.001）。两组的极低密度脂蛋白（VLDLc）无差异。目前的数据表明，血清和胆汁脂蛋白特别是LDLc和HDLc之间存在统计学上的显著相关性（r = +0.67和r = +0.56）。本报告表明，与总胆固醇（59.43%）和甘油三酯（57.15%）水平相比，血清HDLc（67.42%）和LDLc（70.28%）在胆结石形成中起更关键的作用。
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