Maguire M S, Byth W
Department of Psychology, University of Luton, England.
Percept Psychophys. 1998 Feb;60(2):221-6. doi: 10.3758/bf03206031.
The McCollough effect (ME) has been shown to be sensitive to cholinergic agents, being strengthened by hyoscine (antagonist) and weakened by physostigmine (agonist), and possibly to more generalized changes in CNS arousal. We therefore expected the ME to be sensitive to hormonal changes during the menstrual cycle, being strongest in the postovulatory phases when arousal is low. In two experiments we found a highly significant effect of menstrual phase for the normally cycling women, but not for oral contraceptive users: ME strength gradually increased across the cycle, reaching a premenstrual peak. These findings may be explained in terms of hormonally mediated changes in arousal across the menstrual cycle.
麦考勒效应（ME）已被证明对胆碱能药物敏感，受东莨菪碱（拮抗剂）增强，受毒扁豆碱（激动剂）减弱，并且可能对中枢神经系统唤醒的更广泛变化敏感。因此，我们预计ME对月经周期中的激素变化敏感，在排卵后期唤醒水平较低时最强。在两项实验中，我们发现月经周期对正常月经周期的女性有高度显著影响，但对口服避孕药使用者没有影响：ME强度在整个周期中逐渐增加，在经前达到峰值。这些发现可以用月经周期中激素介导的唤醒变化来解释。
