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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Magide A A, Press C M, Myant N B, Mitropoulos K A, Balasubramaniam S

Biochim Biophys Acta. 1976 Aug 23;441(2):302-7. doi: 10.1016/0005-2760(76)90173-9.

The effect of portacaval anastomosis on the metabolism of plasma lipoproteins was investigated in rats. 2. When compared with sham-operated pair-fed controls, plasma high density lipoprotein cholesterol concentration was decreased, plasma low density lipoprotein cholesterol concentration was increased and plasma total cholesterol concentration was unchanged in the portacaval anastomosis rats. Maximal incorporation of [14C]leucine into the total circulating mass of protein was decreased in the very low density lipoprotein and high density lipoprotein fractions and, possibly, in the low density lipoprotein fraction, but there was no change in maximal incorporation into albumin. It is concluded that portacaval anastomosis diminishes the rate of synthesis of high density lipoprotein and very low density lipoprotein proteins and, possibly, of low density lipoprotein proteins.

在大鼠中研究了门腔静脉吻合术对血浆脂蛋白代谢的影响。2. 与假手术配对喂养的对照组相比，门腔静脉吻合术大鼠的血浆高密度脂蛋白胆固醇浓度降低，血浆低密度脂蛋白胆固醇浓度升高，血浆总胆固醇浓度无变化。极低密度脂蛋白和高密度脂蛋白组分以及可能的低密度脂蛋白组分中，[14C]亮氨酸最大掺入总循环蛋白量减少，但白蛋白最大掺入量无变化。得出的结论是，门腔静脉吻合术降低了高密度脂蛋白和极低密度脂蛋白蛋白以及可能的低密度脂蛋白蛋白的合成速率。

Magide A A, Press C M, Myant N B, Mitropoulos K A, Balasubramaniam S

Biochim Biophys Acta. 1976 Aug 23;441(2):302-7. doi: 10.1016/0005-2760(76)90173-9.

The effect of portacaval anastomosis on the metabolism of plasma lipoproteins was investigated in rats. 2. When compared with sham-operated pair-fed controls, plasma high density lipoprotein cholesterol concentration was decreased, plasma low density lipoprotein cholesterol concentration was increased and plasma total cholesterol concentration was unchanged in the portacaval anastomosis rats. Maximal incorporation of [14C]leucine into the total circulating mass of protein was decreased in the very low density lipoprotein and high density lipoprotein fractions and, possibly, in the low density lipoprotein fraction, but there was no change in maximal incorporation into albumin. It is concluded that portacaval anastomosis diminishes the rate of synthesis of high density lipoprotein and very low density lipoprotein proteins and, possibly, of low density lipoprotein proteins.

在大鼠中研究了门腔静脉吻合术对血浆脂蛋白代谢的影响。2. 与假手术配对喂养的对照组相比，门腔静脉吻合术大鼠的血浆高密度脂蛋白胆固醇浓度降低，血浆低密度脂蛋白胆固醇浓度升高，血浆总胆固醇浓度无变化。极低密度脂蛋白和高密度脂蛋白组分以及可能的低密度脂蛋白组分中，[14C]亮氨酸最大掺入总循环蛋白量减少，但白蛋白最大掺入量无变化。得出的结论是，门腔静脉吻合术降低了高密度脂蛋白和极低密度脂蛋白蛋白以及可能的低密度脂蛋白蛋白的合成速率。