Lincoff N S, Rath P P, Hirano M
Department of Neurology and Ophthalmology, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, USA.
J Neuroophthalmol. 1998 Mar;18(1):17-20.
This article describes the effects of topically applied capsaicin (a nociceptive substance-P suppressor) in patients with neuropathic periocular or facial pain. Peripheral neuropathic pain is a major cause of periocular or facial discomfort and usually follows injury to a subcutaneous peripheral nerve. Though the damage is local, the pain tends to radiate. We studied three patients who complained of a 2- to 30-year history of fluctuating pain in the periocular area. All three had an area of point tenderness that responded to the topical application of capsaicin cream.
本文描述了局部应用辣椒素（一种P物质抑制剂）对神经性眼周或面部疼痛患者的影响。周围神经性疼痛是眼周或面部不适的主要原因，通常继发于皮下周围神经损伤。尽管损伤是局部的，但疼痛往往会放射。我们研究了三名患者，他们主诉有2至30年眼周区域疼痛波动的病史。所有三名患者均有一个压痛点区域，该区域对局部应用辣椒素乳膏有反应。
