Kovacs M, Devlin B
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA.
J Child Psychol Psychiatry. 1998 Jan;39(1):47-63.
In this selective review of recent research on internalizing disorders in childhood, we focus on four areas: the predictive validity of the diagnoses of depressive and anxiety disorders, rates of comorbidity, the chronology of onsets of the disorders of interest, and transmission of depressive and anxiety disorders in the pedigrees of affected individuals. To synthesize and reconcile findings in these four areas, we approach the information from a developmental perspective and assume that genetically driven biologic processes play a salient role in the expression of depressive and anxiety disorders in childhood. We also comment on the relevance of findings on children and adolescents to the field of depressive and anxiety disorders in adults and make recommendations for further research.
在本次对儿童内化性障碍近期研究的选择性综述中，我们关注四个领域：抑郁和焦虑障碍诊断的预测效度、共病率、相关障碍的发病时间顺序，以及受影响个体家系中抑郁和焦虑障碍的传递。为了综合和协调这四个领域的研究结果，我们从发展的角度来审视这些信息，并假设基因驱动的生物学过程在儿童抑郁和焦虑障碍的表现中起着显著作用。我们还评论了儿童和青少年研究结果与成人抑郁和焦虑障碍领域的相关性，并提出进一步研究的建议。
