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情感障碍、酒精中毒和精神分裂症的终身自杀风险。

Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia.

作者信息

Inskip H M, Harris E C, Barraclough B

机构信息

MRC Environmental Epidemiology Unit, University of Southampton.

出版信息

Br J Psychiatry. 1998 Jan;172:35-7. doi: 10.1192/bjp.172.1.35.

Abstract

BACKGROUND

The lifetime risks of suicide are generally quoted as 15% for affective disorder and alcoholism and 10% for schizophrenia, based on data from 1921-1975 and on calculations performed before computerised modelling techniques became available. This study recalculates the risk using contemporary data and modern techniques.

METHOD

Twenty-seven mortality studies provided data for affective disorder, 27 for alcohol dependence and 29 for schizophrenia. The proportion of the cohort who had died was plotted against the proportion of deaths from suicide. Modelling techniques fitted curves through the data points extrapolating them to cohort extinction, thus estimating the lifetime risk of suicide for each disorder.

RESULTS

The lifetime risk was estimated at 6% for affective disorder. 7% for alcohol dependence and 4% for schizophrenia.

CONCLUSIONS

The lifetime suicide risk figures often quoted in the literature appear to be too high.

摘要

背景

基于1921年至1975年的数据以及在计算机建模技术出现之前所做的计算,情感障碍和酒精中毒的终身自杀风险通常被引用为15%,精神分裂症为10%。本研究使用当代数据和现代技术重新计算了风险。

方法

27项死亡率研究提供了情感障碍的数据,27项提供了酒精依赖的数据,29项提供了精神分裂症的数据。将队列中死亡的比例与自杀死亡的比例进行绘图。建模技术通过数据点拟合曲线并将其外推至队列灭绝,从而估计每种疾病的终身自杀风险。

结果

情感障碍的终身风险估计为6%,酒精依赖为7%,精神分裂症为4%。

结论

文献中经常引用的终身自杀风险数字似乎过高。

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