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环境控制对维持处于临床缓解期的慢性阻塞性肺病马匹的影响:对肺功能的作用

Environmental control to maintain stabled COPD horses in clinical remission: effects on pulmonary function.

作者信息

Vandenput S, Duvivier D H, Votion D, Art T, Lekeux P

机构信息

Laboratory for Functional Investigation, Faculty of Veterinary Medicine, University of Liège, Belgium.

出版信息

Equine Vet J. 1998 Mar;30(2):93-6. doi: 10.1111/j.2042-3306.1998.tb04466.x.

Abstract

The objective of this study was to test the hypothesis that stabled COPD horses can be maintained in clinical remission by replacing hay by grass silage and bedding made of wood shavings (Period B) and of wheat straw (Period C) during 6 weeks, respectively. At the end of these different periods, the pulmonary function of the horses was assessed by mechanics of breathing and arterial blood analyses. These results were compared to those measured in clinical remission obtained after 2 months in pasture (Period A). No significant difference was observed between these 3 periods neither to values obtained for healthy horses placed during 6 weeks in a hay environment. For all that, COPD horses placed in contact with hay in the same barn developed within mean +/- s.d. 8+/-3 days clinical signs of heaves and significant alterations of pulmonary function parameters.

摘要

本研究的目的是检验以下假设

分别用青贮草料替代干草,并在6周内分别使用刨花(阶段B)和麦秸(阶段C)作为垫料,稳定期慢性阻塞性肺病(COPD)马匹能够维持临床缓解状态。在这些不同阶段结束时,通过呼吸力学和动脉血液分析评估马匹的肺功能。将这些结果与在牧场放牧2个月后获得临床缓解时所测得的结果(阶段A)进行比较。在这三个阶段之间,以及与在干草环境中放置6周的健康马匹所获得的值之间,均未观察到显著差异。尽管如此,在同一畜舍中接触干草的COPD马匹平均在8±3天内出现气喘的临床症状,并且肺功能参数发生显著改变。

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