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马的慢性阻塞性肺疾病。2:治疗

Chronic obstructive pulmonary disease in the horse. 2: Therapy.

作者信息

Thomson J R, McPherson E A

出版信息

Equine Vet J. 1983 Jul;15(3):207-10. doi: 10.1111/j.2042-3306.1983.tb01766.x.

Abstract

The therapy of equine chronic obstructive pulmonary disease (COPD) essentially entails minimising the horse's exposure to the aetiological antigens which are predominantly thermophilic actinomycetes and moulds occurring in hay and straw. This can be achieved, for example, by keeping affected horses permanently out of doors, or when stabled, using shredded paper, wood shavings or peat moss as bedding and feeding a complete cubed diet. There should be no supplementary hay feeding apart from dust-free vacuum-packed hay. Applying such measures generally allows horses to become asymptomatic in seven to 14 days. Bronchodilators and corticosteroids bring about a marked, but temporary, improvement and can be of value in the treatment of acute attacks. The use of oral bronchodilators in combination with environmental control measures may hasten the remission of clinical signs in affected horse. Inhaled sodium cromoglycate can be used prophylactically in asymptomatic horses to prevent the onset of COPD when unavoidable antigen exposure is anticipated.

摘要

马慢性阻塞性肺疾病(COPD)的治疗主要包括尽量减少马暴露于主要为干草和稻草中存在的嗜热放线菌和霉菌等致病抗原。例如,这可以通过让患病马匹长期饲养在户外来实现,或者当马匹圈养时,使用碎纸、刨花或泥炭藓作为垫料,并喂食全价颗粒饲料。除了无尘真空包装的干草外,不应补充喂食其他干草。采取这些措施通常可使马匹在7至14天内无症状。支气管扩张剂和皮质类固醇可带来显著但暂时的改善,对急性发作的治疗可能有价值。口服支气管扩张剂与环境控制措施联合使用可能会加速患病马匹临床症状的缓解。吸入色甘酸钠可预防性用于无症状马匹,以防止在预期不可避免地接触抗原时COPD的发作。

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