Levi M, Guchelaar H J, Woerdenbag H J, Zhu Y P
Department of Internal Medicine, University of Amsterdam, The Netherlands.
Pharm World Sci. 1998 Feb;20(1):43-4. doi: 10.1023/a:1008698811463.
A case is presented of reversible acute hepatitis in a patient using a Chinese herbal tea. Upon identification of the tea mixture Aristolochia species, including A. debilis, which contains the highly toxic aristolochic acid, could be identified. We conclude that the acute hepatitis as described in this patient is most likely to be caused by (one of) the active ingredients of the Chinese herbal tea. Furthermore, this case illustrates that so-called natural products can cause unexpected severe adverse reactions.
本文报告了一例饮用中国凉茶的患者出现可逆性急性肝炎的病例。经鉴定,该茶混合物中含有马兜铃属植物,包括含有剧毒马兜铃酸的青木香。我们得出结论,该患者所描述的急性肝炎很可能是由中国凉茶的活性成分(之一)引起的。此外,该病例表明所谓的天然产品可能会引起意想不到的严重不良反应。