青光眼视网膜小动脉局灶性狭窄的荧光素血管造影相关性
Fluorescein angiographic correlation of focal narrowing of retinal arterioles in glaucoma.
作者信息
Papastathopoulos K I, Jonas J B
机构信息
Department of Ophthalmology and Eye Hospital, University Erlangen-Nürnberg, Germany.
出版信息
Br J Ophthalmol. 1998 Jan;82(1):48-50. doi: 10.1136/bjo.82.1.48.
BACKGROUND
Recent studies have shown that focal narrowing of retinal arterioles in the parapapillary region occurs in eyes with optic neuropathies such as glaucoma. This study evaluated whether these vessel constrictions detected ophthalmoscopically have an equivalent in angiographic imaging of the fundus.
METHODS
Fluorescein angiograms and colour wide angle fundus photographs of 33 patients with open angle glaucoma and 76 subjects with normal optic nerves were examined for focal narrowing of retinal arterioles. The angiograms had primarily been taken for other reasons such as age related macula degeneration.
RESULTS
All focal narrowings of retinal arterioles detected on fundus photographs showed a localised constriction of vessel filling in the fluorescein angiograms. Degree of vessel narrowing on the fundus photographs and degree of constriction of the fluorescein vessel filling were significantly (p < 0.001) correlated with each other.
CONCLUSIONS
Focal narrowing of retinal arterioles in the parapapillary region of eyes with optic neuropathies represents a real stenosis of the vessel lumen and is not due to an ophthalmoscopic artefact.
背景
近期研究表明，在患有青光眼等视神经病变的眼睛中，视乳头旁区域的视网膜小动脉会出现局灶性狭窄。本研究评估了通过检眼镜检测到的这些血管狭窄在眼底血管造影成像中是否有对应表现。
方法
对33例开角型青光眼患者和76例视神经正常的受试者的荧光素血管造影和彩色广角眼底照片进行检查，以观察视网膜小动脉的局灶性狭窄情况。这些血管造影主要是因其他原因（如年龄相关性黄斑变性）而拍摄的。
结果
眼底照片上检测到的所有视网膜小动脉局灶性狭窄在荧光素血管造影中均显示为血管充盈的局限性收缩。眼底照片上的血管狭窄程度与荧光素血管充盈的收缩程度之间存在显著相关性（p < 0.001）。
结论
患有视神经病变的眼睛视乳头旁区域的视网膜小动脉局灶性狭窄代表血管腔的真正狭窄，并非检眼镜假象所致。
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