Cisneros J L, Río R, Palou J
Hospital Asepeyo, Sant Cugat, Barcelona, Spain.
Dermatol Surg. 1998 Mar;24(3):345-50.
The Q-switched neodymium (Nd):YAG laser with quadruple frequency is very effective for the treatment of tattoos, pigmented lesions, and vascular, benign lesions. It is also an option for treating rhytides, scars, and facial pigmentations.
This paper is based on a series of patients with periocular and perioral rhytides, postacne scars, and melanic and vascular eyelid pigmentation who were treated with the Q-switched Nd:YAG laser with quadruple frequency.
The patients were divided in three separate groups: facial wrinkles, postacne scars, and eyelid pigmentation. All were biopsied before and after the laser treatment. Different wavelengths (1064, 650, 585, and 532 nm) were used in order to study the clinical improvement and the histological changes that occurred several weeks following the laser treatment. Additionally, these biopsies aided in observing specific histological characteristics related to applying the different wavelengths by evaluating them along with the clinical results.
Very good results were achieved in the 22 facial wrinkle cases with two treatments. Excellent results were achieved in the 28 postacne patients, and the outcome of the 16 patients with pigmentation of the eyelids were considered good.
The Q-switched Nd:YAG laser with quadruple frequency can be classified as a valid alternative for facial resurfacing. The results obtained are comparable to those with the pulsed carbon dioxide lasers, plus it has the advantage of being effective on vascular lesions.
四倍频调Q钕（Nd）：YAG激光在治疗纹身、色素沉着性病变以及血管性良性病变方面非常有效。它也是治疗皱纹、瘢痕和面部色素沉着的一种选择。
本文基于一系列接受四倍频调Q Nd：YAG激光治疗的患有眼周和口周皱纹、痤疮后瘢痕以及眼睑色素沉着（包括黑色素沉着和血管性色素沉着）的患者。
患者被分为三个独立的组：面部皱纹组、痤疮后瘢痕组和眼睑色素沉着组。所有患者在激光治疗前后均接受活检。使用不同波长（1064、650、585和532nm）以研究激光治疗数周后出现的临床改善情况和组织学变化。此外，这些活检通过将其与临床结果一起评估，有助于观察与应用不同波长相关的特定组织学特征。
22例面部皱纹患者经过两次治疗取得了非常好的效果。28例痤疮后患者取得了优异的效果，16例眼睑色素沉着患者的治疗结果被认为良好。
四倍频调Q Nd：YAG激光可被归类为面部皮肤磨削术的一种有效替代方法。所获得的结果与脉冲二氧化碳激光的结果相当，此外它还具有对血管性病变有效的优势。
