Matsuo T, Masuda I, Matsuo N
Department of Ophthalmology, Okayama University Medical School, Japan.
Jpn J Ophthalmol. 1998 Jan-Feb;42(1):51-5. doi: 10.1016/s0021-5155(97)00102-0.
A 37-year-old man developed geographic choroiditis and retinal vasculitis in the left eye while taking 3.5 mg/day oral prednisolone for rheumatoid arthritis. The choroidal lesions stopped growing when the dose of prednisolone was increased to 60 mg/day, while its tapering resulted in the recurrence and enlargement of the choroidal lesions to the macula. The patient experienced further recurrence twice in the following year. Indocyanine green angiography demonstrated the obstruction of choroidal arteries in addition to the complete obstruction of the choriocapillaris in a fresh lesion. This case was the first to have geographic choroiditis on the background of a systemic inflammatory disease.
一名37岁男性在服用3.5毫克/天口服泼尼松龙治疗类风湿关节炎时,左眼出现地图状脉络膜炎和视网膜血管炎。当泼尼松龙剂量增加至60毫克/天时,脉络膜病变停止发展,而逐渐减量则导致脉络膜病变复发并扩大至黄斑区。该患者在接下来的一年中又复发了两次。吲哚菁绿血管造影显示,除了新鲜病变中脉络膜毛细血管完全阻塞外,脉络膜动脉也有阻塞。该病例是首例在全身性炎症性疾病背景下发生地图状脉络膜炎的病例。