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高血压患者舌下含服硝酸甘油后颈动脉多普勒血流速度模式的变化。

Changes of the carotid artery Doppler flow velocity pattern after sublingual nitroglycerin in patients with hypertension.

作者信息

Jeong J W, Park O K, Park Y K, Tei C, Tanaka N

机构信息

Division of Cardiology, Wonkwang University School of Medicine, Iksan, Korea.

出版信息

Korean J Intern Med. 1998 Feb;13(1):22-6. doi: 10.3904/kjim.1998.13.1.22.

DOI:10.3904/kjim.1998.13.1.22
PMID:9538627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4531938/
Abstract

OBJECTIVE

To evaluate the applicability of carotid Doppler echography for the assessment of changes of peripheral hemodynamics in the hypertensives.

SUBJECTS

28 hypertensives (17 males, 11 females), mean age of 64 yrs and 40 normal controls (24 males, 16 females) mean age of 49 yrs.

METHODS

We recorded the right common carotid arterial Doppler flow velocity (BFV) pattern and measured the peak velocities of the percussion wave (P) and late rising tidal wave (T), the ratio of the two (P/T), the time interval between the two peaks corrected by heart rate (P-Tc), systolic flow velocity integral (FVI) and carotid artery diameter (CAD) before and after 0.4 mg dose of subligual nitroglycerin (NTG).

RESULTS

  1. In hypertensives, the P wave velocity showed lower and P-Tc interval shorter than those of the normal controls at baseline. 2) After NTG, the P-Tc and P/T increased, but the T and FVI decreased significantly in both groups of subjects. 3) The P/T ratio was less significantly increased after NTG in the hypertensives than in the controls. These results suggest that NTG might have been involved in concomitant reduction and delay of the wave reflection from the peripheral vessels, preferentially in the normal subjects than in hypertensives.

CONCLUSIONS

The carotid Doppler echography can be useful for the evaluation of the changes of hemodynamics in the peripheral vessel such as carotid artery in hypertensive subjects.

摘要

目的

评估颈动脉多普勒超声检查在评估高血压患者外周血流动力学变化中的适用性。

对象

28例高血压患者（男性17例，女性11例），平均年龄64岁；40例正常对照者（男性24例，女性16例），平均年龄49岁。

方法

记录右颈总动脉多普勒血流速度（BFV）模式，测量0.4mg舌下硝酸甘油（NTG）给药前后的叩击波（P）和晚升潮波（T）的峰值速度、二者比值（P/T）、经心率校正的双峰时间间隔（P-Tc）、收缩期血流速度积分（FVI）以及颈动脉直径（CAD）。

结果

1）高血压患者在基线时，P波速度低于正常对照者，P-Tc间期短于正常对照者。2）NTG给药后，两组受试者的P-Tc和P/T均升高，但T和FVI均显著降低。3）高血压患者NTG给药后P/T比值升高幅度低于正常对照者。这些结果提示，NTG可能参与了外周血管波反射的减少和延迟，正常受试者比高血压患者更明显。

结论

颈动脉多普勒超声检查有助于评估高血压患者外周血管如颈动脉的血流动力学变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/828fef2a2858/kjim-13-1-22-4f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/17deefe46b13/kjim-13-1-22-4f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/468da0ccd83c/kjim-13-1-22-4f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/8dc12fdbd645/kjim-13-1-22-4f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/7195cbd65b38/kjim-13-1-22-4f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/9d09a9446217/kjim-13-1-22-4f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/828fef2a2858/kjim-13-1-22-4f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/17deefe46b13/kjim-13-1-22-4f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/468da0ccd83c/kjim-13-1-22-4f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/8dc12fdbd645/kjim-13-1-22-4f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/7195cbd65b38/kjim-13-1-22-4f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/9d09a9446217/kjim-13-1-22-4f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ad/4531938/828fef2a2858/kjim-13-1-22-4f6.jpg

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