Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids.
作者信息
Baulieu E E, Robel P
机构信息
Institut National de la Santé et de la Recherche Médicale, U 488, 80 rue du Général Leclerc, 94276 Le Kremlin-Bicêatre Cedex, France.
出版信息
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4089-91. doi: 10.1073/pnas.95.8.4089.
Abstract
摘要
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Neurosteroids Biosynthesis and function.神经甾体的生物合成与功能。
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Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development.脱氢表雄酮：发育过程中新皮质组织的潜在信号分子。
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4678-83. doi: 10.1073/pnas.95.8.4678.
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Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.检测脑胶质肿瘤细胞中不依赖P450c17的脱氢表雄酮（DHEA）生物合成途径。
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2862-7. doi: 10.1073/pnas.95.6.2862.
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Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.神经甾体：老年大鼠认知能力下降取决于海马中硫酸孕烯醇酮水平较低。
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Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors.硫酸脱氢表雄酮通过σ1受体减轻地佐环平诱导的小鼠学习障碍。
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