Frigo P, Lang C, Reisenberger K, Kölbl H, Hirschl A M
Department of Gynecology and Obstetrics, University Hospital of Vienna, Austria.
Obstet Gynecol. 1998 Apr;91(4):615-7. doi: 10.1016/s0029-7844(97)00709-6.
To test the hypothesis that infection with Helicobacter pylori is associated with hyperemesis gravidarum.
From January 1995 to November 1996 we enrolled 105 patients with hyperemesis gravidarum in a prospective study. The Helicobacter serum Immunoglobulin (Ig) G concentrations in these patients were compared with those in asymptomatic gravidas matched for week of gestation.
Positive serum IgG concentrations were found in 95 of the 105 hyperemesis patients (90.5%) compared with 60 of 129 controls (46.5%). A chi2 test showed statistical significance (P < .001). The mean (+/-standard deviation) index percentages of the IgG titers were 74.2+/-23.6% in the hyperemesis group and 24.3+/-4.4% in the control group (P < .01, Student t test).
Infection with H pylori may cause hyperemesis gravidarum.
检验幽门螺杆菌感染与妊娠剧吐相关的假说。
1995年1月至1996年11月，我们对105例妊娠剧吐患者进行了一项前瞻性研究。将这些患者的幽门螺杆菌血清免疫球蛋白（Ig）G浓度与妊娠周数匹配的无症状孕妇的浓度进行比较。
105例妊娠剧吐患者中有95例（90.5%）血清IgG浓度呈阳性，而129例对照组中有60例（46.5%）呈阳性。卡方检验显示具有统计学意义（P <.001）。IgG滴度的平均（±标准差）指数百分比在妊娠剧吐组中为74.2±23.6%，在对照组中为24.3±4.4%（P <.01，Student t检验）。
幽门螺杆菌感染可能导致妊娠剧吐。
