Kaplan S L, Busner J
Saint Louis University School of Medicine, Department of Psychiatry, Wohl Institute, MO 63104, USA.
J Child Adolesc Psychopharmacol. 1997;7(4):275-86. doi: 10.1089/cap.1997.7.275.
To study prescribing practices of inpatient child psychiatrists under 3 auspices of care, 137 medicated patients were compared to 122 nonmedicated patients at a state hospital, a private hospital and a county-university hospital in New York during 1991. Overall, 79% of state, 76% of private, and 68% of county-university hospital patients received at least one dose of psychotropic medication, with the state versus county-university comparison significant (p < 0.05). Significantly more medicated patients at the private hospital (80%) than at the state or county-university hospitals (each 26%) received antidepressants (p's < 0.001). Significantly more county-university (74%) than private (35%) patients received antipsychotic medications, but the proportion of nonpsychotic patients receiving antipsychotic medication was statistically similar across the three hospitals. In nonpsychotic patients, antipsychotic agents were used to treat aggressive behavior. Patients 12 years of age or younger received more stimulants, and patients 13 years of age or older received more lithium (p's < 0.01). In a clinical review of medical charts of medicated patients from the 3 auspices of care, approximately 90% of the medication-treated patients were treated at an acceptable dose level and with an acceptable rationale based on symptom or diagnosis. These and other findings and other suggest that children in state hospitals are not over-medicated in comparison to children in private hospitals or university-county hospitals, and that prescribing practices among the three hospitals, despite their different funding sources, are comparable.
为研究在三种医疗环境下住院儿童精神科医生的处方行为,1991年在纽约的一家州立医院、一家私立医院和一家县立大学医院,对137名接受药物治疗的患者与122名未接受药物治疗的患者进行了比较。总体而言,79%的州立医院患者、76%的私立医院患者和68%的县立大学医院患者至少接受了一剂精神药物治疗,州立医院与县立大学医院之间的比较具有显著性差异(p < 0.05)。私立医院接受抗抑郁药治疗的患者(80%)显著多于州立医院或县立大学医院(均为26%)(p值< 0.001)。接受抗精神病药物治疗的县立大学医院患者(74%)显著多于私立医院患者(35%),但在三家医院中,非精神病患者接受抗精神病药物治疗的比例在统计学上相似。在非精神病患者中,抗精神病药物用于治疗攻击行为。12岁及以下的患者使用更多的兴奋剂,13岁及以上的患者使用更多的锂盐(p值< 0.01)。在对来自三种医疗环境下接受药物治疗患者的病历进行的临床审查中,约90%接受药物治疗的患者是以可接受的剂量水平并基于症状或诊断的合理依据进行治疗的。这些以及其他发现表明,与私立医院或县立大学医院的儿童相比,州立医院的儿童用药不过量,而且尽管三家医院的资金来源不同,但它们的处方行为具有可比性。