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仙台病毒血凝和溶血活性对非抗体抑制剂的不同敏感性

Different sensitivity of hemagglutinating and hemolytic activities of Sendai virus to non-antibody inhibitors.

作者信息

Sinibaldi L, De Stasio A, Mastromarino P, Seganti L, Valenti P, Orsi N

出版信息

Boll Ist Sieroter Milan. 1979 Nov 30;58(5):365-70.

PMID:95432
Abstract

Research was carried out in order to verify if some components of human serum, which are capable of inhibiting the hemagglutination by Sendai virus, are active even towards the hemolysis by the same virus. It was ascertained that both orosomucoid and low-density lipoproteins obtained by floatation had no action on the hemolysis by Sendai virus while lipoproteins precipitated with dextrane sulphate showed a certain inhibiting effect. This action however is not due to lipoproteins but is probably related to some substances used in the method of precipitation.

摘要

进行了研究,以验证人血清中某些能够抑制仙台病毒血凝作用的成分,对同一病毒的溶血作用是否也有活性。已确定通过漂浮获得的血清类粘蛋白和低密度脂蛋白对仙台病毒的溶血作用均无影响,而用硫酸葡聚糖沉淀的脂蛋白则显示出一定的抑制作用。然而,这种作用并非由脂蛋白引起,可能与沉淀方法中使用的某些物质有关。

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