van der Meer J W
Academisch Ziekenhuis, afd. Algemeen Interne Geneeskunde, Nijmegen.
Ned Tijdschr Geneeskd. 1997 Aug 2;141(31):1507-9.
Chronic fatigue syndrome is a controversial disease entity. Opinions range from non-disease via psychiatric disorder to a somatic disturbance. Somatic pathogenetic hypotheses include persisting infections, intoxications, metabolic or immunologic disturbances, nervous system diseases and endocrine pathology. None of these hypotheses has been substantiated as yet. Psychological factors are important in the course of the disorder and can be used in the therapeutic approach of patients with chronic fatigue syndrome.
慢性疲劳综合征是一种存在争议的疾病实体。观点涵盖从非疾病状态到精神障碍再到躯体功能紊乱。躯体发病假说包括持续性感染、中毒、代谢或免疫紊乱、神经系统疾病以及内分泌病变。然而，这些假说目前均未得到证实。心理因素在该疾病过程中很重要，并且可用于慢性疲劳综合征患者的治疗方法中。
