Hadjipavlou A G, Cesani-Vazquez F, Villaneuva-Meyer J, Mader J T, Necessary J T, Crow W, Jensen R E, Chaljub G
Department of Orthopaedics and Rehabilitation, University of Texas Medical Branch at Galveston, Texas, USA.
Am J Orthop (Belle Mead NJ). 1998 Mar;27(3):179-83.
We investigated the role of gallium citrate Ga 67 scanning in diagnosing spondylodiscitis. Scans of 41 patients with suspected spondylodiscitis showed increased radionuclide uptake in 39 patients; these findings correlated with those of magnetic resonance imaging and were proved by biopsy. Two patients with negative findings on gallium scans had been strongly suspected of having spondylodiscitis; biopsy findings in these patients showed degenerative changes. Thirteen patients had negative cultures, while 22 had polygenic infections and 4 had granulomatous infections. Gallium scanning proved to be 100% sensitive, specific, and accurate. The interrater accuracy was excellent. Follow-up scans were used to track therapeutic progress. We recommend complementary bone and gallium scans in cases of suspected spinal infections. If the scan is positive, a biopsy should be done. If the scans are negative, no further investigation is needed.
我们研究了枸橼酸镓Ga 67扫描在诊断脊椎椎间盘炎中的作用。对41例疑似脊椎椎间盘炎患者进行的扫描显示，39例患者的放射性核素摄取增加；这些结果与磁共振成像结果相关，并经活检证实。2例镓扫描结果为阴性的患者曾被高度怀疑患有脊椎椎间盘炎；这些患者的活检结果显示为退行性改变。13例患者培养结果为阴性，22例为多基因感染，4例为肉芽肿性感染。镓扫描的敏感性、特异性和准确性均为100%。评估者间的准确性极佳。随访扫描用于跟踪治疗进展。对于疑似脊柱感染的病例，我们建议进行骨骼和镓扫描。如果扫描结果为阳性，应进行活检。如果扫描结果为阴性，则无需进一步检查。
