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波兰东北部人群中DNA位点HLA - DQα多态性

DNA locus HLA-DQ alpha polymorphism in human population of the north-eastern Poland.

作者信息

Pepiński W, Skawrońska M, Janica J

机构信息

Department of Forensic Medicine, Medical Academy of Białystok.

出版信息

Rocz Akad Med Bialymst. 1996;41(2):277-83.

PMID:9020539
Abstract

Investigations on DNA polymorphism locus HLA-DQ alpha were carried out on a sample of 117 adult unrelated inhabitants from the north-eastern Poland. The polymerase chain reaction and the reverse dot-blot hybridisation were employed to detect 6 different HLA-DQ alpha alleles. Population data on 20 different genotypes served as a basis for statistic evaluation. The results of genotype analysis were in Hardy-Weinberg equilibrium. Other population data were compared.

摘要

对来自波兰东北部的117名成年非亲属居民样本进行了DNA多态性位点HLA - DQα的研究。采用聚合酶链反应和反向点杂交技术检测6种不同的HLA - DQα等位基因。20种不同基因型的群体数据作为统计评估的基础。基因型分析结果符合哈迪-温伯格平衡。并对其他群体数据进行了比较。

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