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间歇性臭氧暴露对墨西哥城哮喘儿童呼气峰值流速和呼吸道症状的影响。

Effects of intermittent ozone exposure on peak expiratory flow and respiratory symptoms among asthmatic children in Mexico City.

作者信息

Romieu I, Meneses F, Ruiz S, Huerta J, Sienra J J, White M, Etzel R, Hernandez M

机构信息

Centro Panamericano de Ecologia Human y Salud, Organization Panamericana de la Salud, Mexico.

出版信息

Arch Environ Health. 1997 Sep-Oct;52(5):368-76. doi: 10.1080/00039899709602213.

DOI:10.1080/00039899709602213
PMID:9546760
Abstract

In a panel study of Mexican children (5-13 y of age) with mild asthma, the authors studied the relationship between ozone exposure and the course of childhood asthma. Decrements in peak expiratory flow rate were associated with ozone, and respiratory symptoms were associated with both ozone level and ambient particulate matter (< 10 microm) level. After the authors adjusted for minimum temperature and autocorrelation in the data, they determined that an increase of 50 ppb in a daily ozone 1-h maximum was related to an 8% increase in cough (95% confidence interval = 2, 15); a 24% increase in phlegm (95% confidence interval = 13, 35); and an 11% increase in low respiratory symptoms index (95% confidence interval = 5, 19). The authors concluded that children with mild asthma who resided in the south of Mexico City were affected adversely by the high ozone ambient levels observed in this area.

摘要

在一项针对患有轻度哮喘的墨西哥儿童(5 - 13岁)的小组研究中,作者研究了臭氧暴露与儿童哮喘病程之间的关系。呼气峰值流速的下降与臭氧有关,呼吸道症状与臭氧水平和环境颗粒物(< 10微米)水平均有关。在作者对数据中的最低温度和自相关性进行校正后,他们确定每日臭氧1小时最大值增加50 ppb与咳嗽增加8%(95%置信区间 = 2, 15)、痰液增加24%(95%置信区间 = 13, 35)以及低呼吸道症状指数增加11%(95%置信区间 = 5, 19)相关。作者得出结论,居住在墨西哥城南部的患有轻度哮喘的儿童受到该地区观测到的高臭氧环境水平的不利影响。

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