Romieu I, Meneses F, Sienra-Monge J J, Huerta J, Ruiz Velasco S, White M C, Etzel R A, Hernandez-Avila M
Centro Panamericano de Ecologia Humana y Salud, Organizacion Panamericana de la Salud, Mexico City.
Am J Epidemiol. 1995 Mar 15;141(6):546-53. doi: 10.1093/oxfordjournals.aje.a117470.
The metropolitan area of Mexico City, Mexico, has serious air pollution problems. Although air contaminants may contribute to clinical asthma, there are at present no data on the relation between air pollution exposure and childhood asthma in Mexico City. The authors reviewed data on emergency visits from January to June 1990 at one major pediatric hospital in Mexico City. They used a Poisson regression model to study the relation between the number of daily emergency visits for asthma and air pollutant levels. The levels of ozone and sulfur dioxide-exposure were significantly associated with the number of emergency visits for asthma. After adjustment for potential confounding factors, the multivariate regression model predicted that an increase of 50 ppb in the 1-hour maximum ozone level would lead to a 43% increase in the number of emergency visits for asthma on the following day. Exposure to high ozone levels (> 110 ppb) for 2 consecutive days increased the number of asthma-related emergency visits by 68 percent. The results of this study suggest that ozone exposure is positively associated with the number of children's emergency visits for asthma in Mexico City.
墨西哥墨西哥城都市区存在严重的空气污染问题。尽管空气污染物可能会导致临床哮喘，但目前尚无关于墨西哥城空气污染暴露与儿童哮喘之间关系的数据。作者回顾了1990年1月至6月期间墨西哥城一家主要儿科医院的急诊数据。他们使用泊松回归模型研究哮喘每日急诊就诊次数与空气污染物水平之间的关系。臭氧和二氧化硫暴露水平与哮喘急诊就诊次数显著相关。在对潜在混杂因素进行调整后，多元回归模型预测，1小时最大臭氧水平每增加50 ppb，次日哮喘急诊就诊次数将增加43%。连续两天暴露于高臭氧水平（>110 ppb）会使与哮喘相关的急诊就诊次数增加68%。这项研究的结果表明，在墨西哥城，臭氧暴露与儿童哮喘急诊就诊次数呈正相关。
