曲菌素，一种来自子囊菌小巢状毛盘菌的生物活性氮杂蒽酮。
Trichoflectin, a bioactive azaphilone from the ascomycete Trichopezizella nidulus.
作者信息
Thines E, Anke H, Sterner O
机构信息
Department of Biotechnology, University of Kaiserslautern, Germany.
出版信息
J Nat Prod. 1998 Feb;61(2):306-8. doi: 10.1021/np970469g.
PMID:9548866
Abstract
Trichoflectin (1), a new azaphilone belonging to the deflectin series, 6-deoxy-7-0-demethyl-3,4-anhydrofusarubin (2), and 6-deoxy-3,4-anhydrofusarubin (3) were isolated from submerged cultures of the ascomycete Trichopezizella nidulus. All compounds showed antimicrobial activity and inhibited dihydroxynaphthalene melanin biosynthesis in fungi. The structure of trichoflectin (1) was elucidated by spectroscopic methods.
摘要
曲菌素（1）是一种属于偏菌素系列的新氮杂蒽酮，6-脱氧-7-O-去甲基-3,4-脱水镰孢菌素（2）和6-脱氧-3,4-脱水镰孢菌素（3）是从子囊菌鸟巢状毛盘菌的深层培养物中分离得到的。所有化合物均表现出抗菌活性，并能抑制真菌中二羟基萘黑色素的生物合成。通过光谱方法阐明了曲菌素（1）的结构。
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