Shaker H S, Hassouna M
Division of Urology, Toronto Hospital, University of Toronto, Ontario, Canada.
J Urol. 1998 May;159(5):1476-8. doi: 10.1097/00005392-199805000-00017.
Sacral root neuromodulation is becoming a superior alternative to the standard treatment of idiopathic nonobstructive urinary retention. We report results in 20 successive patients who underwent sacral foramen implantation to restore bladder function.
After an initial, thorough baseline assessment 20 patients 19.43 to 55.66 years old with idiopathic nonobstructive urinary retention underwent percutaneous nerve evaluation. Response was assessed by a detailed voiding diary. Responders underwent implantation with an S3 foramen implant, and were followed 1, 3 and 6 months postoperatively, and every 6 months thereafter.
Sacral root neuromodulation restored voiding capability in these patients. Bladders were emptied with minimal post-void residual urine, which decreased from 78.3 to 5.5 to 10.2% of the total voided volume from baseline to postoperative followup. These results were reflected in uroflowmetry and pressure-flow studies, which were almost normal after implantation. Furthermore, the urinary tract infection rate decreased significantly and associated pelvic pain improved substantially. The Beck depression inventory and SF-36 quality of life questionnaire indicated some improvement but reached significance in only 1 item. In addition, cystometrography showed no significant difference after 6 months of implantation compared with baseline values. Complications were minimal and within expectations.
Sacral root neuromodulation is an appealing, successful modality for nonobstructive urinary retention. Only patients who have a good response to percutaneous nerve evaluation are candidates for implantation. The high efficacy in patients who undergo implantation, relative simplicity of the procedure and low complication rate make this a treatment breakthrough in this difficult group.
骶神经根神经调节正成为特发性非梗阻性尿潴留标准治疗的一种更好替代方法。我们报告连续20例接受骶孔植入以恢复膀胱功能患者的结果。
在进行初步全面的基线评估后,20例年龄在19.43至55.66岁之间的特发性非梗阻性尿潴留患者接受经皮神经评估。通过详细的排尿日记评估反应情况。有反应者接受S3孔植入物植入,并在术后1、3和6个月进行随访,此后每6个月随访一次。
骶神经根神经调节恢复了这些患者的排尿能力。膀胱排空后残余尿量极少,从基线到术后随访,残余尿量占总排尿量的比例从78.3%降至5.5%至10.2%。这些结果在尿流率和压力 - 流率研究中得到体现,植入后这些指标几乎正常。此外,尿路感染率显著降低,相关盆腔疼痛明显改善。贝克抑郁量表和SF - 36生活质量问卷显示有一定改善,但仅在1项上达到显著水平。另外,植入6个月后的膀胱测压与基线值相比无显著差异。并发症极少且在预期范围内。
骶神经根神经调节是治疗非梗阻性尿潴留的一种有吸引力且成功的方法。只有对经皮神经评估有良好反应的患者才是植入的候选者。植入患者的高疗效、相对简单的操作过程和低并发症发生率使其成为这一困难群体治疗上的突破。