居住在墨西哥城的儿童淋巴瘤流行病学。

Epidemiology of lymphomas in children residing in Mexico City.

作者信息

Mendoza-Sánchez H F, Quintana-Sánchez J A, Rivera-Márquez H, Mejía-Domínguez A M, Fajardo-Gutiérrez A

机构信息

Unidad de Investigación Médica en Epidemiología Clínica, Instituto Mexicano del Seguro Social, México, D.F., México.

出版信息

Arch Med Res. 1998 Spring;29(1):67-73.

PMID:9556925

Abstract

BACKGROUND

The aim of this paper is to present the epidemiological characteristics of time, subject and place of lymphomas in children residing in Mexico City, Mexico (MC).

METHODS

The type of study was a retrospective hospital survey. All records of children with lymphomas registered between 1982 and 1991 at the main hospitals that treat children with cancer in MC were reviewed. Neoplasms were classified into Hodgkin's disease (HD) and non-Hodgkin's lymphomas (NonHL). Trend and incidence by sex, age and area of residence in MC were evaluated. Time of diagnosis, as well as parental occupation and educational level, were registered.

RESULTS

A trend was only observed for HD in the total group (r:0.62; P = 0.05). In 1991, incidence for HD was 6.12 (rates x 10(6)) and 3.87 for NonHL. The highest average incidence was found in children 5-9 years of age (5.40) for HD, and in the age groups of 1-4 and 5-9 (3.10 and 3.33, respectively), for NonHL. Incidence was higher among boys for both lymphoma categories, but the male-to-female ratio was much higher in HD. Time of diagnosis, incidence in terms of place of residence, and parental educational level and occupation also differed from one lymphoma category to the other.

CONCLUSION

The epidemiology of HD is different from that of NonHL, both showing a pattern similar to that of Latin American children.

摘要

背景

本文旨在呈现墨西哥城（MC）儿童淋巴瘤在时间、对象和地点方面的流行病学特征。

方法

本研究类型为回顾性医院调查。对1982年至1991年间在MC主要治疗儿童癌症的医院登记的所有儿童淋巴瘤记录进行了审查。肿瘤被分为霍奇金病（HD）和非霍奇金淋巴瘤（NonHL）。评估了MC中按性别、年龄和居住地区划分的趋势和发病率。记录了诊断时间以及父母的职业和教育水平。

结果

仅在总组中观察到HD的一种趋势（r：0.62；P = 0.05）。1991年，HD的发病率为6.12（发病率×10⁶），NonHL为3.87。HD在5至9岁儿童中平均发病率最高（5.40），NonHL在1至4岁和5至9岁年龄组中最高（分别为3.10和3.33）。两种淋巴瘤类型中男孩的发病率均较高，但HD中的男女比例更高。诊断时间、按居住地点划分的发病率以及父母的教育水平和职业在不同淋巴瘤类型之间也存在差异。