Mejía-Aranguré J M, Fajardo-Gutiérrez A, Bernáldez-Ríos R, Farfán-Canto J M, Ortíz-Fernández A, Martínez-García M D
Unidad de Investigación Médica en Epidemiología Clínica, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D.F.
Arch Med Res. 1996 Summer;27(2):223-7.
The objective of this study was to identify the tendency of acute leukemia among children in Mexico City from 1982 to 1991. A hospital survey was performed. Medical records of children under 15 years of age with a diagnosis of acute leukemia were reviewed. The cases were chosen from hospitals which provide medical attention to children with cancer in Mexico City. The annual incidence rate (AIR) was calculated in general, by sex, age groups (under 1 year of age, from 1 to 4 years, 5 to 9 years and 10 to 14 years) and standardized with the world population. The trend was evaluated with Spearman's correlation method. Acute lymphoblastic leukemia showed a significantly increasing trend during the study period. The AIR was 7.75 (per million) in 1982 and 22.19 (per million) in 1991. For age groups a tendency to increase was observed in females of age group 1 to 4 years and in males of age group 10 to 14 years. Acute non-lymphoblastic leukemia did not display a specific trend. In conclusion, acute lymphoblastic leukemia shows a tendency to increase in the children of Mexico City.
本研究的目的是确定1982年至1991年墨西哥城儿童急性白血病的发病趋势。开展了一项医院调查。对诊断为急性白血病的15岁以下儿童的病历进行了审查。这些病例选自墨西哥城为患癌儿童提供医疗服务的医院。总体上按性别、年龄组（1岁以下、1至4岁、5至9岁和10至14岁）计算年发病率（AIR），并根据世界人口进行标准化。采用Spearman相关法评估趋势。在研究期间，急性淋巴细胞白血病呈显著上升趋势。1982年年发病率为7.75（每百万），1991年为22.19（每百万）。在年龄组方面，1至4岁的女性和10至14岁的男性呈现上升趋势。急性非淋巴细胞白血病未呈现特定趋势。总之，墨西哥城儿童的急性淋巴细胞白血病呈上升趋势。
