Grieshaber M K, Völkel S
Institut für Zoophysiologie, Heinrich-Heine-Universität, Düsseldorf, Germany.
Annu Rev Physiol. 1998;60:33-53. doi: 10.1146/annurev.physiol.60.1.33.
Many aquatic animal species can survive sulfide exposure to some extent through oxidation of the sulfide, which results mainly in thiosulfate. In several species, sulfide oxidation is localized in the mitochondria and is accompanied by ATP synthesis. In addition, blood-based and intracellular compounds can augment sulfide oxidation. The formation of thiosulfate requires oxygen, which results in an increase in oxygen consumption of some species. If not all sulfide is detoxified, cytochrome C oxidase is inhibited. Under these conditions, a sulfide-dependent anaerobic energy metabolism commences.
许多水生动物物种能够通过硫化物的氧化在一定程度上耐受硫化物暴露，这种氧化主要产生硫代硫酸盐。在一些物种中，硫化物氧化定位于线粒体中，并伴有ATP合成。此外，血液中的化合物和细胞内的化合物可以增强硫化物氧化。硫代硫酸盐的形成需要氧气，这导致一些物种的耗氧量增加。如果并非所有硫化物都被解毒，细胞色素C氧化酶就会受到抑制。在这些条件下，一种依赖硫化物的无氧能量代谢就会开始。
