Santi E, Bral M
Advanced Education Program in Periodontics, New York University College of Dentistry, New York, USA.
Int J Periodontics Restorative Dent. 1998 Feb;18(1):80-5.
The clinical and histologic responses to periodontal treatment of gingival enlargements, induced when cyclosporine and nifedipine were administered singly or in combination, were evaluated. A significant correlation was noted between plaque, gingivitis, and gingival overgrowth. Severity of enlargement appeared to be greater in patients on combined therapy. All treatment approaches such as scaling, root planning, gingivectomy, and periodontal flaps, and a combination of therapies, were effective in the management of gingival overgrowth up to 1 year after completion of treatment. Adjunctive use of chlorhexidine was found to be beneficial.
评估了单独或联合使用环孢素和硝苯地平引起的牙龈增生的牙周治疗的临床和组织学反应。菌斑、牙龈炎和牙龈过度生长之间存在显著相关性。联合治疗的患者牙龈增生的严重程度似乎更高。所有治疗方法，如洁治、根面平整、牙龈切除术和牙周翻瓣术，以及联合治疗，在治疗完成后长达1年的时间里对牙龈过度生长的管理都是有效的。发现辅助使用氯己定是有益的。
