• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童期血管畸形和血管瘤的间质钕钇铝石榴石激光光凝术

Interstitial Nd:YAG photocoagulation for vascular malformations and hemangiomas in childhood.

作者信息

Clymer M A, Fortune D S, Reinisch L, Toriumi D M, Werkhaven J A, Ries W R

机构信息

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tenn 37232-2559, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 1998 Apr;124(4):431-6. doi: 10.1001/archotol.124.4.431.

DOI:10.1001/archotol.124.4.431
PMID:9559692
Abstract

BACKGROUND

Vascular malformations and cavernous hemangiomas are common in childhood. Although cavernous hemangiomas may resolve spontaneously, aggressive intervention is required when their growth could damage vital adjacent structures, such as the orbit, nose, or tongue.

OBJECTIVE

To evaluate the efficacy of interstitial Nd:YAG photocoagulation as an adjunct to intralesional and systemic corticosteroids for treatment of hemangiomas and vascular malformations that had failed to respond to other therapies.

DESIGN

Prospective, nonrandomized trial.

SETTING

Two referral practices of facial plastic and reconstructive surgery in tertiary care, academic medical centers.

PATIENTS

Ten consecutive pediatric patients with either hemangioma or vascular malformation of the head and neck.

INTERVENTION

Laser photocoagulation with an interstitial technique. The Nd:YAG fiber was introduced into the lesion via a 14-gauge angiocatheter needle, and the laser fiber was advanced as coagulation proceeded within the tissue.

MAIN OUTCOME MEASURES

Decrease in the area of the target lesion, amount of energy applied, and number of treatments required to achieve reduction in size.

RESULTS

Long-term follow-up demonstrated regression of the lesion in all 10 patients with good cosmetic results. The range of reduction in size was 20% to 98%. No reexpansion of the lesions was noted after a mean follow-up of 13 months.

CONCLUSIONS

Interstitial photocoagulation of hemangiomas and vascular malformations is an effective treatment for carefully selected patients. When properly applied, this technique can achieve reduction in the size of these lesions without compromising cosmesis.

摘要

背景

血管畸形和海绵状血管瘤在儿童期很常见。尽管海绵状血管瘤可能会自发消退,但当其生长可能损害重要的相邻结构,如眼眶、鼻子或舌头时,则需要积极干预。

目的

评估间质Nd:YAG光凝作为病灶内和全身使用皮质类固醇的辅助手段,用于治疗对其他疗法无反应的血管瘤和血管畸形的疗效。

设计

前瞻性、非随机试验。

地点

三级医疗学术医学中心的两家面部整形和重建外科转诊机构。

患者

连续10例头颈部患有血管瘤或血管畸形的儿科患者。

干预

采用间质技术进行激光光凝。通过14号血管造影导管针将Nd:YAG光纤插入病灶,并随着组织内凝固的进行推进激光光纤。

主要观察指标

目标病灶面积的减小、应用的能量以及使病灶缩小所需的治疗次数。

结果

长期随访显示,所有10例患者的病灶均消退,美容效果良好。病灶缩小范围为20%至98%。平均随访13个月后,未发现病灶再次扩大。

结论

对于经过精心挑选的患者,间质光凝治疗血管瘤和血管畸形是一种有效的治疗方法。正确应用该技术可缩小这些病灶的大小,且不影响美观。

相似文献

1
Interstitial Nd:YAG photocoagulation for vascular malformations and hemangiomas in childhood.儿童期血管畸形和血管瘤的间质钕钇铝石榴石激光光凝术
Arch Otolaryngol Head Neck Surg. 1998 Apr;124(4):431-6. doi: 10.1001/archotol.124.4.431.
2
Neodymium-YAG Laser for hemangiomas and vascular malformations -- long term results.钕钇铝石榴石激光治疗血管瘤和血管畸形——长期疗效
J Dtsch Dermatol Ges. 2005 Jun;3(6):436-40. doi: 10.1111/j.1610-0387.2005.05723.x.
3
[Interstitial Nd:YAG laser therapy. Color-Doppler imaging (CDI)-guided laser therapy of hemangiomas and vascular malformations].[间质Nd:YAG激光治疗。彩色多普勒成像(CDI)引导下的血管瘤和血管畸形激光治疗]
HNO. 2003 Jan;51(1):46-51. doi: 10.1007/s00106-002-0664-2.
4
[Treatment of cavernous hemangiomas with the neodymium:YAG laser].[钕钇铝石榴石激光治疗海绵状血管瘤]
Laryngorhinootologie. 1997 May;76(5):284-8. doi: 10.1055/s-2007-997428.
5
Laser photocoagulation of vascular malformations of the tongue.
Laryngoscope. 1986 May;96(5):537-41. doi: 10.1288/00005537-198605000-00013.
6
Intralesional laser therapy of extensive hemangiomas in 100 consecutive pediatric patients.
Ann Plast Surg. 2000 Feb;44(2):188-94. doi: 10.1097/00000637-200044020-00011.
7
A preliminary study of the combined effect of neodymium: YAG laser photocoagulation and direct steroid instillation in the treatment of capillary/cavernous hemangiomas of infancy.钕钇铝石榴石激光光凝与直接注射类固醇联合治疗婴儿毛细/海绵状血管瘤的初步研究
Ann Plast Surg. 1989 Feb;22(2):94-104.
8
Ultrasound-guided interstitial Nd: YAG laser treatment of voluminous hemangiomas and vascular malformations in 92 patients.超声引导下Nd:YAG激光间质治疗92例巨大血管瘤和血管畸形
Laryngoscope. 1998 Apr;108(4 Pt 1):463-70. doi: 10.1097/00005537-199804000-00001.
9
Argon and YAG laser photocoagulation and excision of hemangiomas and vascular malformations of the nose.氩激光和钇铝石榴石激光光凝及鼻血管瘤和血管畸形切除术
West J Med. 1995 Aug;163(2):122-7.
10
Percutaneous photocoagulation of deep vascular lesions using a fiberoptic laser wand.使用光纤激光棒对深部血管病变进行经皮光凝术。
Ann Plast Surg. 1992 Aug;29(2):143-8. doi: 10.1097/00000637-199208000-00008.

引用本文的文献

1
Bleeding cavernous hemangioma of lower lip: a case report.下唇海绵状血管瘤出血:一例报告
Ann Med Surg (Lond). 2023 Mar 15;85(5):1867-1869. doi: 10.1097/MS9.0000000000000292. eCollection 2023 May.
2
Evaluation of the Efficacy and Safety Profile of Long-Pulsed 1064 Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) Laser in Hemangioma and Vascular Malformation in Darker Skin Types.长脉冲1064钕:钇铝石榴石(Nd:YAG)激光治疗深色皮肤类型血管瘤和血管畸形的疗效及安全性评估
Cureus. 2022 Jun 8;14(6):e25742. doi: 10.7759/cureus.25742. eCollection 2022 Jun.
3
Intra-operative sclerotherapy for treatment of a head and neck venous malformation.
术中硬化治疗头颈部静脉畸形
Acta Otorhinolaryngol Ital. 2015 Feb;35(1):62-5.
4
A xenograft animal model of human arteriovenous malformations.一种人类动静脉畸形的异种移植动物模型。
Orphanet J Rare Dis. 2013 Dec 30;8:199. doi: 10.1186/1750-1172-8-199.
5
Long term follow-up of intralesional laser photocoagulation (ILP) for hemangioma patients.血管瘤患者瘤内激光光凝术(ILP)的长期随访
Laser Ther. 2011;20(4):255-7. doi: 10.5978/islsm.11-or-03.
6
A giant compound hemangioma of lower lip.
J Oral Maxillofac Pathol. 2012 Sep;16(3):438-40. doi: 10.4103/0973-029X.102512.
7
Periocular laser complications.眼周激光并发症。
Semin Plast Surg. 2007 Feb;21(1):74-9. doi: 10.1055/s-2007-967752.
8
Treatment of Vascular Lesions of the Tongue with Nd:YAG Laser.用钕钇铝石榴石激光治疗舌部血管性病变。
Case Rep Med. 2009;2009:795363. doi: 10.1155/2009/795363. Epub 2009 Dec 22.
9
Treatment of hemangiomas in children using a Nd:YAG laser in conjunction with ice cooling of the epidermis: techniques and results.使用Nd:YAG激光结合表皮冰敷治疗儿童血管瘤:技术与结果
BMC Pediatr. 2003 Apr 12;3:2. doi: 10.1186/1471-2431-3-2.