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儿童期血管畸形和血管瘤的间质钕钇铝石榴石激光光凝术

Interstitial Nd:YAG photocoagulation for vascular malformations and hemangiomas in childhood.

作者信息

Clymer M A, Fortune D S, Reinisch L, Toriumi D M, Werkhaven J A, Ries W R

机构信息

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tenn 37232-2559, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 1998 Apr;124(4):431-6. doi: 10.1001/archotol.124.4.431.

Abstract

BACKGROUND

Vascular malformations and cavernous hemangiomas are common in childhood. Although cavernous hemangiomas may resolve spontaneously, aggressive intervention is required when their growth could damage vital adjacent structures, such as the orbit, nose, or tongue.

OBJECTIVE

To evaluate the efficacy of interstitial Nd:YAG photocoagulation as an adjunct to intralesional and systemic corticosteroids for treatment of hemangiomas and vascular malformations that had failed to respond to other therapies.

DESIGN

Prospective, nonrandomized trial.

SETTING

Two referral practices of facial plastic and reconstructive surgery in tertiary care, academic medical centers.

PATIENTS

Ten consecutive pediatric patients with either hemangioma or vascular malformation of the head and neck.

INTERVENTION

Laser photocoagulation with an interstitial technique. The Nd:YAG fiber was introduced into the lesion via a 14-gauge angiocatheter needle, and the laser fiber was advanced as coagulation proceeded within the tissue.

MAIN OUTCOME MEASURES

Decrease in the area of the target lesion, amount of energy applied, and number of treatments required to achieve reduction in size.

RESULTS

Long-term follow-up demonstrated regression of the lesion in all 10 patients with good cosmetic results. The range of reduction in size was 20% to 98%. No reexpansion of the lesions was noted after a mean follow-up of 13 months.

CONCLUSIONS

Interstitial photocoagulation of hemangiomas and vascular malformations is an effective treatment for carefully selected patients. When properly applied, this technique can achieve reduction in the size of these lesions without compromising cosmesis.

摘要

背景

血管畸形和海绵状血管瘤在儿童期很常见。尽管海绵状血管瘤可能会自发消退,但当其生长可能损害重要的相邻结构,如眼眶、鼻子或舌头时,则需要积极干预。

目的

评估间质Nd:YAG光凝作为病灶内和全身使用皮质类固醇的辅助手段,用于治疗对其他疗法无反应的血管瘤和血管畸形的疗效。

设计

前瞻性、非随机试验。

地点

三级医疗学术医学中心的两家面部整形和重建外科转诊机构。

患者

连续10例头颈部患有血管瘤或血管畸形的儿科患者。

干预

采用间质技术进行激光光凝。通过14号血管造影导管针将Nd:YAG光纤插入病灶,并随着组织内凝固的进行推进激光光纤。

主要观察指标

目标病灶面积的减小、应用的能量以及使病灶缩小所需的治疗次数。

结果

长期随访显示,所有10例患者的病灶均消退,美容效果良好。病灶缩小范围为20%至98%。平均随访13个月后,未发现病灶再次扩大。

结论

对于经过精心挑选的患者,间质光凝治疗血管瘤和血管畸形是一种有效的治疗方法。正确应用该技术可缩小这些病灶的大小,且不影响美观。

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