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儿童感冒用抗生素:哪些医生是高处方者?

Antibiotics for colds in children: who are the high prescribers?

作者信息

Mainous A G, Hueston W J, Love M M

机构信息

Department of Family Practice, University of Kentucky, Lexington, USA.

出版信息

Arch Pediatr Adolesc Med. 1998 Apr;152(4):349-52.

PMID:9559710
Abstract

OBJECTIVE

To examine physician characteristics associated with being a high prescriber of antibiotics for pediatric upper respiratory tract infections (URIs).

DESIGN AND SETTING

Analysis of 34624 episodes of care for URIs in children (younger than 18 years) in the Kentucky Medicaid program from July 1, 1995, to June 30, 1996.

PARTICIPANTS

Primary care physicians with at least 25 episodes of care (n=205). The proportion of patients with URIs receiving antibiotics stratified the sample into low (< or =25th percentile) and high (> or =75th percentile) antibiotic prescribers.

MAIN OUTCOME MEASURES

Bivariate analyses were computed comparing the high and low prescribers. A logistic regression model was computed for likelihood of being a high prescriber by number of URI episodes, proportion of patients receiving antibiotics that were broad spectrum, years since medical school graduation, physician gender, rural/urban practice, and specialty.

RESULTS

The high prescriber group (n=52) included data from 11899 episodes of care, with a mean prescribing rate of 80%. The low prescriber group (n=55) included data from 5396 episodes, with a mean prescribing rate of 16%. High prescribers were significantly more years away from medical school graduation (27 vs 19 years; P<.001) and had managed significantly more URI episodes than low prescribers (229 vs 98; P=.001). In the logistic regression, compared with pediatricians, the odds ratios of being a high prescriber were 409 (95% confidence interval [CI], 29-7276) for family practitioners and 318 (95% CI, 17-6125) for other primary care physicians.

CONCLUSION

With the rise of antibiotic-resistant bacteria, more focused training regarding treatment of URIs is warranted in residency and in continuing medical education forums.

摘要

目的

研究与小儿上呼吸道感染(URI)抗生素高处方率相关的医生特征。

设计与背景

对1995年7月1日至1996年6月30日肯塔基医疗补助计划中18岁以下儿童的34624例URI护理病例进行分析。

参与者

至少有25例护理病例的初级保健医生(n = 205)。根据接受抗生素治疗的URI患者比例,将样本分为低(≤第25百分位数)和高(≥第75百分位数)抗生素处方医生。

主要观察指标

对高、低处方医生进行双变量分析。通过URI病例数、接受广谱抗生素治疗的患者比例、自医学院毕业年限、医生性别、城乡执业情况和专业,计算成为高处方医生可能性的逻辑回归模型。

结果

高处方医生组(n = 52)包括11899例护理病例的数据,平均处方率为80%。低处方医生组(n = 55)包括5396例病例的数据,平均处方率为16%。高处方医生自医学院毕业的年限显著更长(27年对19年;P <.001),且管理的URI病例数显著多于低处方医生(229例对98例;P =.001)。在逻辑回归中,与儿科医生相比,家庭医生成为高处方医生的优势比为409(95%置信区间[CI],29 - 7276),其他初级保健医生为318(95%CI,17 - 6125)。

结论

随着抗生素耐药菌的增加,在住院医师培训和继续医学教育论坛中,有必要针对URI治疗进行更有针对性的培训。

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