Mendelson G, Aronow W S, Ahn C
Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York, USA.
J Am Geriatr Soc. 1998 Apr;46(4):481-3. doi: 10.1111/j.1532-5415.1998.tb02470.x.
To investigate the prevalence of coronary artery disease (CAD), atherothrombotic brain infarction (ABI), and peripheral arterial disease (PAD) in older Hispanics and the association with risk factors in this population.
A retrospective analysis of charts from all Hispanics seen during January 1996 through July 1997 at an academic hospital-based geriatrics practice.
An academic, hospital-based, primary care geriatrics practice staffed by fellows in a geriatrics training program and by full-time faculty geriatricians.
One hundred sixty women and 53 men, mean age 80 +/- 8 years (range 64 to 100), were included in the study.
Of 213 Hispanics in the study, 59 (28%) had documented CAD, 43 (20%) had ABI, 34 (16%) had PAD, and 90 (42%) had either CAD, ABI, or PAD. Serum total cholesterol and triglycerides were measured in 202 of 213 subjects (95%). Serum high-density lipoprotein cholesterol was measured in 137 of 213 patients (64%). Other risk factor data were documented in all patients. Multiple logistic regression analysis performed in 202 patients using the variables age, gender, cigarette smoking, hypertension, diabetes mellitus, obesity, serum total cholesterol, and serum triglycerides showed statistically significant associations between prevalent CAD, ABI, or PAD and age (P = .002, odds ratio (OR) = 1.083), cigarette smoking (P = .002, (OR) = 3.865), hypertension (P = .007, (OR) = 2.749), diabetes mellitus (P = .028, (OR) = 2.386), obesity (P = .014, (OR) = 2.608), serum total cholesterol (P < 0.001, (OR) = 1.025), and serum triglycerides (P = .017, (OR) = .993).
Either CAD, ABI, or PAD was present in 42% of 213 older Hispanics. There were statistically significant associations between prevalent CAD, ABI, or PAD in older Hispanics and risk factors, including age, cigarette smoking, hypertension, diabetes mellitus, obesity, and serum total cholesterol.
调查老年西班牙裔人群中冠状动脉疾病（CAD）、动脉粥样硬化血栓形成性脑梗死（ABI）和外周动脉疾病（PAD）的患病率及其与该人群危险因素的关联。
对1996年1月至1997年7月期间在一家学术性医院老年医学诊所就诊的所有西班牙裔患者的病历进行回顾性分析。
一家学术性、以医院为基础的初级保健老年医学诊所，由老年医学培训项目的研究员和全职老年医学医生组成。
本研究纳入了160名女性和53名男性，平均年龄80±8岁（范围64至100岁）。
在213名西班牙裔研究对象中，59人（28%）有记录显示患有CAD，43人（20%）患有ABI，34人（16%）患有PAD，90人（42%）患有CAD、ABI或PAD中的一种。213名研究对象中的202人（95%）测量了血清总胆固醇和甘油三酯。213名患者中的137人（64%）测量了血清高密度脂蛋白胆固醇。所有患者均记录了其他危险因素数据。对202名患者进行多因素逻辑回归分析，采用年龄、性别、吸烟、高血压、糖尿病、肥胖、血清总胆固醇和血清甘油三酯等变量，结果显示，CAD、ABI或PAD的患病率与年龄（P = 0.002，比值比（OR）= 1.083）、吸烟（P = 0.002，OR = 3.865）、高血压（P = 0.007，OR = 2.749）、糖尿病（P = 0.028，OR = 2.386）、肥胖（P = 0.014，OR = 2.608）、血清总胆固醇（P < 0.001，OR = 1.025）和血清甘油三酯（P = 0.017，OR = 0.993）之间存在统计学显著关联。
在213名老年西班牙裔人群中，42%的人患有CAD、ABI或PAD中的一种。老年西班牙裔人群中CAD、ABI或PAD的患病率与年龄、吸烟、高血压、糖尿病、肥胖和血清总胆固醇等危险因素之间存在统计学显著关联。
