剂量卡对医院内直接观察下的结核病治疗依从性的影响。
The effect of dosage cards on compliance with directly observed tuberculosis therapy in hospital.
作者信息
Sonnenberg P, Ross M H, Shearer S C, Murray J
机构信息
Department of Community Health, University of the Witwatersrand, Johannesburg, South Africa.
出版信息
Int J Tuberc Lung Dis. 1998 Feb;2(2):168-71.
We evaluated the effect of a dosage card signed by both patient and health worker on compliance in a tuberculosis ward. Compliance was assessed by testing a urine specimen from each patient for the presence of isoniazid and rifampicin pre-intervention and at two weeks, six weeks and 16 months post-intervention. Pre-intervention compliance was 62% and increased to 88%, 91% and 93% in the short, medium and long-term, respectively (P = 0.03, P = 0.02, P < 0.01). The assumption that directly observed therapy is successfully practised in hospital is not always correct. Simple inexpensive measures can improve compliance and have an impact on tuberculosis control.
我们评估了患者和医护人员共同签署的剂量卡对结核病病房患者依从性的影响。通过检测每位患者干预前以及干预后两周、六周和16个月的尿液样本中异烟肼和利福平的存在情况来评估依从性。干预前的依从率为62%，在短期、中期和长期分别提高到88%、91%和93%（P = 0.03，P = 0.02，P < 0.01）。认为在医院成功实施直接观察治疗的假设并不总是正确的。简单廉价的措施可以提高依从性并对结核病控制产生影响。
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