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全肘关节置换术后感染。

Infection after total elbow arthroplasty.

作者信息

Yamaguchi K, Adams R A, Morrey B F

机构信息

Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

出版信息

J Bone Joint Surg Am. 1998 Apr;80(4):481-91. doi: 10.2106/00004623-199804000-00004.

Abstract

The purpose of this study was to review our experience with the treatment of twenty-five infections (in twenty-five patients) after total elbow arthroplasty and to examine indications for salvage of the prosthesis compared with those for resection arthroplasty. The patients were divided into three groups on the basis of treatment. Group I comprised fourteen patients who were managed with multiple, extensive irrigation and debridement procedures with retention of the original components. The primary indication for retention of the prosthesis was evidence that it was well fixed as determined both radiographically and intraoperatively. Group II comprised six patients who had removal of the prosthesis and debridement followed by immediate or staged reimplantation. Group III comprised five patients who were managed with resection arthroplasty. The infection was successfully eradicated in seven of the fourteen elbows that had salvage of the prosthesis with irrigation and debridement. The results were strongly dependent on the causative organism; attempts at debridement failed in the four elbows that were infected with Staphylococcus epidermidis compared with three of the ten that were infected with another organism. Four of the six patients in Group II had successful reimplantation of a prosthesis; in three, the infection had been caused by an organism other than Staphylococcus epidermidis. Only one of the three patients who had a Staphylococcus epidermidis infection had a successful reimplantation. None of the five patients who had a resection arthroplasty had signs of infection at the latest follow-up examination. We concluded that salvage of the prosthesis with extensive irrigation and debridement in the presence of an infection about the elbow can be reasonably successful if the infecting organism is not Staphylococcus epidermidis and if the components are well fixed. When removal of the components is warranted, staged reimplantation can also be highly successful when the infecting organism is not Staphylococcus epidermidis. However, the repeated operations necessary to retain a prosthesis and the high rates of complications seen with this approach--and the relatively good rates of satisfaction obtained with resection arthroplasty--suggest that resection arthroplasty remains the procedure of choice in medically frail patients or in patients for whom function of the elbow is less of a concern.

摘要

本研究的目的是回顾我们治疗全肘关节置换术后25例感染(25名患者)的经验,并探讨与切除关节成形术相比假体挽救的指征。根据治疗方法将患者分为三组。第一组包括14名患者,他们接受了多次广泛的冲洗和清创术,保留了原有的假体组件。保留假体的主要指征是影像学和术中均证实假体固定良好。第二组包括6名患者,他们接受了假体取出和清创术,随后立即或分期进行再植入。第三组包括5名接受切除关节成形术的患者。在14例通过冲洗和清创挽救假体的肘关节中,7例感染成功根除。结果很大程度上取决于致病微生物;与感染其他微生物的10例中的3例相比,4例感染表皮葡萄球菌的肘关节清创尝试失败。第二组6名患者中有4例成功再植入假体;其中3例感染由表皮葡萄球菌以外的微生物引起。感染表皮葡萄球菌的3例患者中只有1例成功再植入。在最新的随访检查中,接受切除关节成形术的5名患者均无感染迹象。我们得出结论,如果感染微生物不是表皮葡萄球菌且假体组件固定良好,在肘关节感染时通过广泛冲洗和清创挽救假体可能相当成功。当有必要取出假体组件时,如果感染微生物不是表皮葡萄球菌,分期再植入也可能非常成功。然而,保留假体所需的反复手术以及这种方法出现的高并发症发生率——以及切除关节成形术相对较高的满意度——表明切除关节成形术仍然是身体虚弱患者或对肘关节功能不太在意的患者的首选手术方法。

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