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7767名希腊学龄儿童的血清胆固醇和甘油三酯分布情况

Serum cholesterol and triglyceride distribution in 7767 school-aged Greek children.

作者信息

Schulpis K, Karikas G A

机构信息

Institute of Child Health, Aghia Sophia Children's Hospital, Athens, Greece.

出版信息

Pediatrics. 1998 May;101(5):861-4. doi: 10.1542/peds.101.5.861.

Abstract

OBJECTIVE

To elucidate associations of age and sex with serum cholesterol and triglyceride levels and to provide for the first time percentile distribution data for pediatric lipids.

PARTICIPANTS AND METHODS

A high sample of 7767 (3980 boys, 3787 girls) fasting schoolchildren, 6 to 14 years of age, were studied in Athens, Greece.

RESULTS

The mean cholesterol ranged from 157 to 174 mg/dL for boys and from 158 to 172 mg/dL for girls peaking at 9 years of age for both sexes. Triglyceride levels also tended to increase gradually and to peak at 11 years of age for both sexes. The high-density lipoprotein cholesterol levels were highest at 9 years of age for both sexes and the low-density lipoprotein cholesterol levels also tended to peak at 9 years of age for boys and at 8 years of age for girls. Atherogenic indices ranged from 1.54 to 1.68 for boys and 1. 51 to 1.85 for girls.

CONCLUSION

According to these findings, it could be suggested that diet changes in the Greek population, especially in children and adolescents, living in big cities is significantly influencing their total cholesterol profiles throughout the last 10 years.

摘要

目的

阐明年龄和性别与血清胆固醇及甘油三酯水平之间的关联,并首次提供儿童血脂的百分位数分布数据。

参与者与方法

在希腊雅典对7767名(3980名男孩,3787名女孩)6至14岁的空腹学童进行了大规模研究。

结果

男孩的平均胆固醇水平在157至174毫克/分升之间,女孩在158至172毫克/分升之间,两性均在9岁时达到峰值。甘油三酯水平也呈逐渐上升趋势,两性均在11岁时达到峰值。高密度脂蛋白胆固醇水平在两性9岁时最高,低密度脂蛋白胆固醇水平在男孩9岁、女孩8岁时也趋于达到峰值。男孩的致动脉粥样化指数在1.54至1.68之间,女孩在1.51至1.85之间。

结论

根据这些研究结果,可认为希腊人群,尤其是生活在大城市的儿童和青少年的饮食变化在过去10年中对他们的总胆固醇状况产生了显著影响。

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