Suter D M, Forscher P
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520-8103, USA.
Curr Opin Neurobiol. 1998 Feb;8(1):106-16. doi: 10.1016/s0959-4388(98)80014-7.
It has become increasingly evident that growth cone guidance depends on the concerted actions of cytoskeletal proteins, molecular motors and cell adhesion molecules. Recent studies suggest that modulation of coupling between extracellular substrates and intracellular cytoskeletal networks via cell surface receptors is an important mechanism for regulating directed neuronal growth.
越来越明显的是，生长锥导向依赖于细胞骨架蛋白、分子马达和细胞粘附分子的协同作用。最近的研究表明，通过细胞表面受体调节细胞外基质与细胞内细胞骨架网络之间的偶联是调节神经元定向生长的重要机制。
