Hurley L S, Cosens G, Theriault L L
J Nutr. 1976 Sep;106(9):1254-60. doi: 10.1093/jn/106.9.1254.
The effect of severe magnesium deficiency on plasma magnesium levels in pregnant and nonpregnant rats and on reproduction was investigated. Magnesium deficiency produced a rapid fall in plasma magnesium concentration, in both pregnant and nonpregnant rats. At term, all implantation sites of pregnant rats fed a diet severely deficient in magnesium showed total fetal resorption. When pregnant females were fed the magnesium deficient diet only between days 6 and 14 of gestation, there was a high incidence of resorptions and gross malformations were seen in full term fetuses. The results demonstrate the rapidity of the effects of severe magnesium deficiency in pregnant rats and indicate the importance of the element for embryonic development.
研究了严重镁缺乏对妊娠和非妊娠大鼠血浆镁水平及生殖的影响。镁缺乏导致妊娠和非妊娠大鼠的血浆镁浓度迅速下降。足月时，喂食严重缺镁饮食的妊娠大鼠的所有着床部位均出现完全的胎儿吸收。当妊娠雌性大鼠仅在妊娠第6至14天喂食缺镁饮食时，吸收发生率很高，足月胎儿出现严重畸形。结果表明严重镁缺乏对妊娠大鼠影响迅速，并表明该元素对胚胎发育的重要性。
