Delank K W, Stoll W
Department of Otorhinolaryngology, Westfälische Wilhelms-Universität, Münster, Germany.
Rhinology. 1998 Mar;36(1):15-9.
One hundred and fifteen patients suffering from chronic sinusitis were observed to analyse the prevalence of olfactory dysfunction and the influence of FESS. Pre-operative questionnaires were supplemented by examination of olfactory thresholds and discrimination. Pre-operatively, 58% of the collective were aware or complained of any olfactory deficit. However, the olfactory tests demonstrated that of the collective 52% were hyposmic and 31% anosmic. Eight per cent of the hyposmic patients presented with an isolated reduction of their ability to discriminate odours. Post-operative improvements were found in 70%. Normosmia was post-operatively achieved in 25% of the hyposmic patients, but only in 5% of the anosmic patients. Olfaction changed to the worse in 8% after FESS. Therefore, the prevalence of olfactory dysfunction in chronic sinusitis is pre-operatively higher, and the rate of improvement is lower than generally assumed. The extent of sinus disease as measured by the degree of intranasal polyposis correlates with olfactory dysfunction. Resections of the middle turbinate may have a negative effect on olfaction, due to damage to the olfactory fila or alteration of the normal aerodynamic pattern within the olfactory cleft. However, this hypothesis is based on a few observations and needs to be verified by further investigations.
观察了115例慢性鼻窦炎患者,以分析嗅觉功能障碍的患病率及功能性鼻内镜鼻窦手术(FESS)的影响。术前问卷辅以嗅觉阈值和辨别力检查。术前,58%的患者意识到或抱怨有任何嗅觉缺陷。然而,嗅觉测试显示,52%的患者嗅觉减退,31%的患者嗅觉丧失。8%的嗅觉减退患者仅表现为气味辨别能力下降。术后70%的患者有改善。25%的嗅觉减退患者术后恢复正常嗅觉,但嗅觉丧失患者中只有5%恢复正常。FESS术后8%的患者嗅觉变差。因此,慢性鼻窦炎患者术前嗅觉功能障碍的患病率较高,改善率低于一般认为的水平。通过鼻息肉程度衡量的鼻窦疾病范围与嗅觉功能障碍相关。中鼻甲切除术可能对嗅觉有负面影响,这是由于嗅丝受损或嗅裂内正常空气动力学模式改变所致。然而,这一假设基于少数观察结果,需要进一步研究加以验证。